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1

Protéinose alvéolaire révélatrice d’une maladie de la télomérase

S. Marchand-Adam, B. Diot, P. Magro, A. De Muret, C. Guignabert, B. Grandchamp, A. Toutain, P. Diot

Journal:

Revue des Maladies Respiratoires

Year:

2012

Language:

french

File:

PDF, 59 KB

french, 2012

2

Pulmonary arterial remodeling induced by a Th2 immune response

Daley, E., Emson, C., Guignabert, C., de Waal Malefyt, R., Louten, J., Kurup, V. P., Hogaboam, C., Taraseviciene-Stewart, L., Voelkel, N. F., Rabinovitch, M., Grunig, E., Grunig, G.

Journal:

Journal of Experimental Medicine

Year:

2008

Language:

english

File:

PDF, 3.52 MB

english, 2008

3

Bone morphogenetic protein signalling in heritable versus idiopathic pulmonary hypertension

Dewachter, L., Adnot, S., Guignabert, C., Tu, L., Marcos, E., Fadel, E., Humbert, M., Dartevelle, P., Simonneau, G., Naeije, R., Eddahibi, S.

Journal:

European Respiratory Journal

Year:

2009

Language:

english

File:

PDF, 501 KB

english, 2009

4

Precision medicine and personalising therapy in pulmonary hypertension: seeing the light from the dawn of a new era

Savale, Laurent, Guignabert, Christophe, Weatherald, Jason, Humbert, Marc

Journal:

European Respiratory Review

Year:

2018

Language:

english

File:

PDF, 347 KB

english, 2018

5

ACE2 as therapy for pulmonary arterial hypertension: the good outweighs the bad

Guignabert, Christophe, de Man, Frances, Lombès, Marc

Journal:

European Respiratory Journal

Year:

2018

Language:

english

File:

PDF, 352 KB

english, 2018

6

Nintedanib improves cardiac fibrosis but leaves pulmonary vascular remodeling unaltered in experimental pulmonary hypertension

Rol, Nina, de Raaf, Michiel A, Sun, Xiaoqing, Kuiper, Vincent P, da Silva Gonçalves Bos, Denielli, Happé, Chris, Kurakula, Kondababu, Dickhoff, Chris, Thuillet, Raphael, Tu, Ly, Guignabert, Christophe

Journal:

Cardiovascular Research

Year:

2018

Language:

english

File:

PDF, 1.93 MB

english, 2018

7

Developmental expression of LC3α and β: Absence of fibronectin or autophagy phenotype in LC3β knockout mice

Gordon M. Cann, Christophe Guignabert, Lihua Ying, Niru Deshpande, Janine M. Bekker, Lingli Wang, Bin Zhou, Marlene Rabinovitch

Journal:

Developmental Dynamics

Year:

2008

Language:

english

File:

PDF, 597 KB

english, 2008

8

Leptine et dysfonction endothéliale dans l’immunopathologie de l’hypertension artérielle pulmonaire idiopathique

A. Huertas, L. Tu, C. Guignabert, N. Gambaryan, B. Girerd, F. Perros, D. Montani, S. Cohen-Kaminsky, M. Humbert

Journal:

Revue des Maladies Respiratoires

Year:

2012

Language:

french

File:

PDF, 52 KB

french, 2012

9

Hypertension artérielle pulmonaire induite par le dasatinib (dual Src/Abl kinase inhibitor)

D. Montani, E. Bergot, S. Günther, L. Savale, A. Bergeron, A. Bourdin, H. Bouvaist, M. Canuet, C. Pison, M. Macro, P. Poubeau, D. Natali, C. Guignabert, F. Perros, D.-S. O’callaghan, X. Jais, G. Zalcm

Journal:

Revue des Maladies Respiratoires

Year:

2012

Language:

french

File:

PDF, 65 KB

french, 2012

10

Leptin and regulatory T-lymphocytes in idiopathic pulmonary arterial hypertension

Huertas, A., Tu, L., Gambaryan, N., Girerd, B., Perros, F., Montani, D., Fabre, D., Fadel, E., Eddahibi, S., Cohen-Kaminsky, S., Guignabert, C., Humbert, M.

Journal:

European Respiratory Journal

Year:

2012

Language:

english

File:

PDF, 443 KB

english, 2012

11

Inhibition of Transforming Growth Factor β Worsens Elastin Degradation in a Murine Model of Kawasaki Disease

Cristina M. Alvira, Christophe Guignabert, Yu-Mee Kim, Chihhsin Chen, Lingli Wang, Trang T. Duong, Rae S.M. Yeung, Dean Y. Li, Marlene Rabinovitch

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 3.14 MB

english, 2011

12

Activation de Rho kinase par sérotonylation intracellulaire de la petite protéine G RhoA dans l’hypertension artérielle pulmonaire

C. Agard, C. Guilluy, S. Eddahibi, C. Guignabert, M. Izikki, L. Tu, L. Savale, M. Humbert, E. Fadel, S. Adnot, G. Loirand, P. Pacaud

Journal:

La Revue de Médecine Interne

Year:

2009

Language:

french

File:

PDF, 74 KB

french, 2009

13

Dual Role for Plasminogen Activator Inhibitor Type 1 as Soluble and as Matricellular Regulator of Epithelial Alveolar Cell Wound Healing

François Maquerlot, Stephane Galiacy, Michel Malo, Christophe Guignabert, Daniel A. Lawrence, Maria-Pia d'Ortho, Georgia Barlovatz-Meimon

Journal:

The American Journal of Pathology

Year:

2006

Language:

english

File:

PDF, 859 KB

english, 2006

14

Genome-wide association analysis identifies a susceptibility locus for pulmonary arterial hypertension

Germain, Marine, Eyries, Mélanie, Montani, David, Poirier, Odette, Girerd, Barbara, Dorfmüller, Peter, Coulet, Florence, Nadaud, Sophie, Maugenre, Svetlana, Guignabert, Christophe, Carpentier, Wassila

Journal:

Nature Genetics

Year:

2013

File:

PDF, 652 KB

2013

15

Reply: The Renin–Angiotensin System in Pulmonary Hypertension

de Man, Frances S., Vonk Noordegraaf, Anton, Humbert, Marc, Guignabert, Christophe

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2013

Language:

english

File:

PDF, 69 KB

english, 2013

16

Relevant Issues in the Pathology and Pathobiology of Pulmonary Hypertension

Tuder, Rubin M., Archer, Stephen L., Dorfmüller, Peter, Erzurum, Serpil C., Guignabert, Christophe, Michelakis, Evangelos, Rabinovitch, Marlene, Schermuly, Ralph, Stenmark, Kurt R., Morrell, Nicholas

Journal:

Journal of the American College of Cardiology

Year:

2013

Language:

english

File:

PDF, 602 KB

english, 2013

17

Targeted therapies in pulmonary arterial hypertension

Montani, David, Chaumais, Marie-Camille, Guignabert, Christophe, Günther, Sven, Girerd, Barbara, Jaïs, Xavier, Algalarrondo, Vincent, Price, Laura C., Savale, Laurent, Sitbon, Olivier, Simonneau, Géra

Journal:

Pharmacology & Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.41 MB

english, 2014

18

AINHUM

Sanchez, O., Dewachter, L., Guignabert, C., Fadel, E., Marcos, E., Humbert, M., Simonneau, G., Adnot, S., Eddahibi, S.

Journal:

Year:

1975

Language:

english

File:

PDF, 304 KB

english, 1975

19

OBSTETRICAL SOCIETY OF LONDON.

Sanchez, O., Dewachter, L., Guignabert, C., Fadel, E., Marcos, E., Humbert, M., Simonneau, G., Adnot, S., Eddahibi, S.

Journal:

Year:

1885

Language:

english

File:

PDF, 431 KB

english, 1885

20

086 Altered Endothelin-1 (ET1) synthesis and ET1 receptors expression and function in idiopathic pulmonary hypertension: influence of BMPRII mutations

Sanchez, O., Dewachter, L., Guignabert, C., Fadel, E., Marcos, E., Humbert, M., Simonneau, G., Adnot, S., Eddahibi, S.

Journal:

Revue des Maladies Respiratoires

Year:

2007

Language:

english

File:

PDF, 63 KB

english, 2007

21

Protéinose alvéolaire révélatrice d’une maladie de la télomérase

Diot, B., Marchand-Adam, S., Magro, P., De Muret, A., Guignabert, C., Grandchamp, B., Toutain, A., Diot, P.

Journal:

Revue des Maladies Respiratoires

Year:

2012

Language:

french

File:

PDF, 51 KB

french, 2012

22

Physiopathologie de l’hypertension artérielle pulmonaire : des progrès et des attentes

Montani, D., Guignabert, C., Perros, F., Humbert, M.

Journal:

Revue des Maladies Respiratoires

Year:

2012

Language:

french

File:

PDF, 235 KB

french, 2012

23

107 Mice overexpressing the 5-hydroxytryptamine transporter in smooth muscle cells spontaneously develop pulmonary hypertension

Guignabert, C., Li, Z., Hanoune, N., Tu, L., Raffestin, B., Rodman, D., Hamon, M., Adnot, S., Eddahibi, S.

Journal:

Revue des Maladies Respiratoires

Year:

2005

Language:

english

File:

PDF, 341 KB

english, 2005

24

Inflammation and Immunity in the Pathogenesis of Pulmonary Arterial Hypertension

Rabinovitch, M., Guignabert, C., Humbert, M., Nicolls, M. R.

Journal:

Circulation Research

Year:

2014

Language:

english

File:

PDF, 1.62 MB

english, 2014

25

Serotonin Transporter Inhibition Prevents and Reverses Monocrotaline-Induced Pulmonary Hypertension in Rats

Journal:

Year:

2005

Language:

english

File:

PDF, 797 KB

english, 2005

26

Contribution des péricytes dans le remodelage vasculaire associé à l’hypertension artérielle pulmonaire

Ricard, N., Tu, L., Huertas, A., Phan, C., Le Hiress, M., Fadel, E., Humbert, M., Guignabert, C.

Journal:

Revue des Maladies Respiratoires

Year:

2014

File:

PDF, 64 KB

2014

27

Effects of broad spectrum tyrosine kinase inhibitor on pulmonary circulation homeostasis

Seferian, A., Phan, C., Tu, L., Huertas, A., Sattler, C., Le Hiress, M., Simonneau, G., Humbert, M., Montani, D., Guignabert, C.

Journal:

Revue des Maladies Respiratoires

Year:

2014

Language:

english

File:

PDF, 108 KB

english, 2014

28

Leptin receptor deficiency restores immune function of regulatory T lymphocytes and inhibits hypoxia-induced pulmonary hypertension

Huertas, A., Tu, L., Le Hiress, M., Ricard, N., Thuillet, R., Phan, C., Humbert, M., Guignabert, C.

Journal:

Revue des Maladies Respiratoires

Year:

2014

File:

PDF, 127 KB

2014

29

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] A29. PATHOGENESIS OF PULMONARY HYPERTENSION - Autoimmunity And Pulmonary Arterial Hypertension: The Role Of Leptin

Huertas, Alice, Tu, Ly, Gambaryan, Natalia, Girerd, Barbara, Montani, David, Perros, Frédéric, Cohen-Kaminsky, Sylvia, Guignabert, Christophe, Humbert, Marc

Year:

2012

Language:

english

File:

PDF, 20 KB

english, 2012

30

MIF/CD74 actively contributes to endothelial pro-inflammatory phenotype in pulmonary arterial hypertension

Le Hiress, M., Tu, L., Ricard, N., Phan, C., Thuillet, R., Seferian, A., Fadel, E., Montani, D., Humbert, M., Huertas, A., Guignabert, C.

Journal:

Revue des Maladies Respiratoires

Year:

2014

File:

PDF, 85 KB

2014

31

Immune Dysregulation and Endothelial Dysfunction in Pulmonary Arterial Hypertension: A Complex Interplay

Huertas, A., Perros, F., Tu, L., Cohen-Kaminsky, S., Montani, D., Dorfmuller, P., Guignabert, C., Humbert, M.

Journal:

Year:

2014

Language:

english

File:

PDF, 963 KB

english, 2014

32

Clinical Pharmacology of Endothelin Receptor Antagonists Used in the Treatment of Pulmonary Arterial Hypertension

Chaumais, Marie-Camille, Guignabert, Christophe, Savale, Laurent, Jaïs, Xavier, Boucly, Athénaïs, Montani, David, Simonneau, Gérald, Humbert, Marc, Sitbon, Olivier

Journal:

American Journal of Cardiovascular Drugs

Year:

2015

Language:

english

File:

PDF, 801 KB

english, 2015

33

Right Ventricular Diastolic Impairment in Patients With Pulmonary Arterial Hypertension

Rain, S., Handoko, M. L., Trip, P., Gan, C. T.-J., Westerhof, N., Stienen, G. J., Paulus, W. J., Ottenheijm, C. A. C., Marcus, J. T., Dorfmuller, P., Guignabert, C., Humbert, M., MacDonald, P., dos Re

Journal:

Year:

2013

Language:

english

File:

PDF, 1.42 MB

english, 2013

34

Expression of TLR9 in tumor-infiltrating mononuclear cells enhances angiogenesis and is associated with a worse survival in lung cancer

Belmont, Laure, Rabbe, Nathalie, Antoine, Martine, Cathelin, Dominique, Guignabert, Christophe, Kurie, Jonathan, Cadranel, Jacques, Wislez, Marie

Journal:

International Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 725 KB

english, 2014

35

Angiomatoid fibrous histiocytoma of the pulmonary artery: a multidisciplinary discussion

Ghigna, Maria-Rosa, Hamdi, Sarah, Petitpretz, Patrick, Rohnean, Adela, Florea, Valentina, Mussot, Sacha, Dartevelle, Philippe, Dorfmuller, Peter, Tu, Ly, Thuillet, Raphaël, Guignabert, Christophe, Tho

Journal:

Year:

2014

Language:

english

File:

PDF, 642 KB

english, 2014

36

Increased Pericyte Coverage Mediated by Endothelial-Derived Fibroblast Growth Factor-2 and Interleukin-6 Is a Source of Smooth Muscle-Like Cells in Pulmonary Hypertension

Ricard, N., Tu, L., Le Hiress, M., Huertas, A., Phan, C., Thuillet, R., Sattler, C., Fadel, E., Seferian, A., Montani, D., Dorfmuller, P., Humbert, M., Guignabert, C.

Journal:

Year:

2014

Language:

english

File:

PDF, 6.55 MB

english, 2014

37

Transgenic Mice Overexpressing the 5-Hydroxytryptamine Transporter Gene in Smooth Muscle Develop Pulmonary Hypertension

Journal:

Circulation Research

Year:

2006

Language:

english

File:

PDF, 449 KB

english, 2006

38

Therapeutic Efficacy of AAV1.SERCA2a in Monocrotaline-Induced Pulmonary Arterial Hypertension

Hadri, L., Kratlian, R. G., Benard, L., Maron, B. A., Dorfmuller, P., Ladage, D., Guignabert, C., Ishikawa, K., Aguero, J., Ibanez, B., Turnbull, I. C., Kohlbrenner, E., Liang, L., Zsebo, K., Humbert,

Journal:

Year:

2013

Language:

english

File:

PDF, 1.82 MB

english, 2013

39

SM22 -targeted deletion of bone morphogenetic protein receptor 1A in mice impairs cardiac and vascular development, and influences organogenesis

El-Bizri, N., Guignabert, C., Wang, L., Cheng, A., Stankunas, K., Chang, C.-P., Mishina, Y., Rabinovitch, M.

Journal:

Development (The Company of Biologists)

Year:

2008

Language:

english

File:

PDF, 4.80 MB

english, 2008

40

Cellular microparticles in the pathogenesis of pulmonary hypertension

Amabile, N., Guignabert, C., Montani, D., Yeghiazarians, Y., Boulanger, C. M., Humbert, M.

Journal:

European Respiratory Journal

Year:

2013

Language:

english

File:

PDF, 786 KB

english, 2013

41

S100A4 and Bone Morphogenetic Protein-2 Codependently Induce Vascular Smooth Muscle Cell Migration via Phospho-Extracellular Signal-Regulated Kinase and Chloride Intracellular Channel 4

Spiekerkoetter, E., Guignabert, C., de Jesus Perez, V., Alastalo, T.-P., Powers, J. M., Wang, L., Lawrie, A., Ambartsumian, N., Schmidt, A.-M., Berryman, M., Ashley, R. H., Rabinovitch, M.

Journal:

Circulation Research

Year:

2009

Language:

english

File:

PDF, 6.74 MB

english, 2009

42

Smooth Muscle Protein 22 -Mediated Patchy Deletion of Bmpr1a Impairs Cardiac Contractility but Protects Against Pulmonary Vascular Remodeling

El-Bizri, N., Wang, L., Merklinger, S. L., Guignabert, C., Desai, T., Urashima, T., Sheikh, A. Y., Knutsen, R. H., Mecham, R. P., Mishina, Y., Rabinovitch, M.

Journal:

Circulation Research

Year:

2008

Language:

english

File:

PDF, 1.11 MB

english, 2008

43

Leptin signalling system as a target for pulmonary arterial hypertension therapy

Huertas, A., Tu, L., Thuillet, R., Le Hiress, M., Phan, C., Ricard, N., Nadaud, S., Fadel, E., Humbert, M., Guignabert, C.

Journal:

European Respiratory Journal

Year:

2015

Language:

english

File:

PDF, 1.37 MB

english, 2015

44

New Molecular Targets of Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension

Guignabert, Christophe, Tu, Ly, Girerd, Barbara, Ricard, Nicolas, Huertas, Alice, Montani, David, Humbert, Marc

Journal:

Year:

2015

Language:

english

File:

PDF, 1.14 MB

english, 2015

45

Dysfonction endothéliale pulmonaire et hypertension artérielle pulmonaire associée au dasatinib

Phan, C., Seferian, A., Huertas, A., Sattler, C., Tu, L., Thuillet, R., Le Hiress, M., Savale, L., Montani, D., Humbert, M., Guignabert, C.

Journal:

Revue des Maladies Respiratoires

Year:

2015

Language:

english

File:

PDF, 71 KB

english, 2015

46

Inhibition of HIF/Ob/ObR-b axis reverses experimental pulmonary hypertension

Huertas, A., Tu, L., Thuillet, R., Le Hiress, M., Phan, C., Humbert, M., Guignabert, C.

Journal:

Revue des Maladies Respiratoires

Year:

2015

Language:

english

File:

PDF, 59 KB

english, 2015

47

A comparative histological study of pulmonary vascular lesions in lungs of patients with idiopathic or heritable PAH

Ghigna, M.-R., Guignabert, C., Mercier, O., Fadel, E., Tu, L., Simonneau, G., Humbert, M., Dorfmüller, P.

Journal:

Revue des Maladies Respiratoires

Year:

2015

File:

PDF, 54 KB

2015

48

Dichloroacetate treatment partially regresses established pulmonary hypertension in mice with SM22 -targeted overexpression of the serotonin transporter

Guignabert, C., Tu, L., Izikki, M., Dewachter, L., Zadigue, P., Humbert, M., Adnot, S., Fadel, E., Eddahibi, S.

Journal:

The FASEB Journal

Year:

2009

Language:

english

File:

PDF, 1.26 MB

english, 2009

49

Role of Nerve Growth Factor in Development and Persistence of Experimental Pulmonary Hypertension

Freund-Michel, Véronique, Cardoso Dos Santos, Marcelina, Guignabert, Christophe, Montani, David, Phan, Carole, Coste, Florence, Tu, Ly, Dubois, Mathilde, Girerd, Barbara, Courtois, Arnaud, Humbert, Ma

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2015

Language:

english

File:

PDF, 4.68 MB

english, 2015

50

Key roles of Src family tyrosine kinases in the integrity of the pulmonary vascular bed

Guignabert, C., Montani, D.

Journal:

European Respiratory Journal

Year:

2013

Language:

english

File:

PDF, 123 KB

english, 2013